Biologia komputerowa (bioinformatyka, proteomika, biologia strukturalna, sekwencjonowanie, itp.):

• uczenie maszynowe (deep learning, ANN, SVM, algorytmy genetyczne)


• rozwój narzędzi i baz danych bioinformatycznych


• regiony nieuporządkowane białek


• analiza danych z sekwencjonowania (NGS)


• znaczenie polimorfizmu nukleotydów (SNP)


• bioinformatyka strukturalna i obliczeniowa


• modeleowanie struktur białek


• analiza sekwencji białek i RNA

Working in computational biology (proteomics, protein structural biology, NGS, bioinformatics, etc.):

• advanced machine learning (deep learning, ANN, SVM, genetic algorithms)


• development of bioinformatics tools for protein and RNA


• intrinsic protein disorder and its function in biological systems


• next-generation sequencing (NGS) data analysis


• single nucleotide polymorphism (SNP) influence on human diseases


• structural bioinformatics and structural biology


• protein structure modeling


• protein and RNA sequence analysis

Finished projects:

• Proteome-pI 2.0 - isoelectricpointdb2.mimuw.edu.pl - Proteome Isoelectric Point Database 2.0 (the data for 61 million sequences from 20,115 proteomes) the publication cited >20 times since 2022


• IPC 2.0 - ipc2.mimuw.edu.pl - prediction of isoelectric point and pKa dissociation constants using deep learning and SVR, cited >80 times since 2021


• Proteome-pI - isoelectricpointdb.org - Proteome Isoelectric Point Database (the database contains the data for >21 million sequences from 5,029 proteomes calculated by 18 methods, cited >250 times since 2016)


• IPC - isoelectric.org - Isoelectric Point Calculator, the publication cited >350 times since 2016


• MetaDisorder - iimcb.genesilico.pl/metadisorder - prediction of intrinsic disorder in proteins (the best method according to CASP beating >20 other methods for protein disorder prediction in a blind test, cited >350 times since 2012

Finished projects:

• Proteome-pI 2.0 - isoelectricpointdb2.mimuw.edu.pl - Proteome Isoelectric Point Database 2.0 (the data for 61 million sequences from 20,115 proteomes) the publication cited >20 times since 2022


• IPC 2.0 - ipc2.mimuw.edu.pl - prediction of isoelectric point and pKa dissociation constants using deep learning and SVR, cited >80 times since 2021


• Proteome-pI - isoelectricpointdb.org - Proteome Isoelectric Point Database (the database contains the data for >21 million sequences from 5,029 proteomes calculated by 18 methods, cited >250 times since 2016)


• IPC - isoelectric.org - Isoelectric Point Calculator, the publication cited >350 times since 2016


• MetaDisorder - iimcb.genesilico.pl/metadisorder - prediction of intrinsic disorder in proteins (the best method according to CASP beating >20 other methods for protein disorder prediction in a blind test, cited >350 times since 2012